Editor Name: Dr. Marinos A.
Pericleous
Country: UK, London
University: University of Surrey
Designation: PhD (hepatology)
Department: Department of Clinical and Experimental Medicine
Email: drpericleous@gmail.com
BIOGRAPHY:
QUALIFICATIONS AND EDUCATION
October 2015- September 2019: PhD (hepatology); Department of
Clinical and Experimental Medicine; University of Surrey
April 2017: Gastroenterology speciality certificate exam (SCE
July 2010: MRCP (UK)
June 2007: MBBS; Royal Free and University College Medical School;
Merit
August 2004: BSc (Hons) Neuroscience with Basic Medical Sciences;
University College London; 2:1
March 2001: Theory of Music (Distinction); Royal College of Music
August 2000: Attained the rank of Sergeant Major in the Military
Forces (26-month term in office)
June 1997: National Academy of Music (Distinction A+)
AWARDS, PRIZES AND RECOGNITION
Top national recruiter in NIHR portfolio of studies for hepatology
2018/19
Outstanding Poster Rosette UEG meeting, Vienna, October 2018
Travel Award for UEG week, Vienna, October 2018
Intercept Practice to Policy award (‚¬25,000); 2016
Falk Foundation travel grant to attend the Falk Symposium New
Treatment Targets in Gut and Liver Disease; Switzerland, October 2016
BSG Alistair McIntyre Prize for Improving Gastroenterology
Training for developing the regional research trainee network for KSS; June
2016
First Prize for my poster and presentation at the Buckinghamshire
Foundation Forum for my work on management of electrolyte imbalances; June 2015
Norgine/BSG/DDF bursary for trainees, to attend the 2015 DDF
meeting in London
Falk Foundation travel grant to attend the Falk Symposium in œAutoimmune
diseases of the Liver; Lisbon, May 2015
BSG award for IBS Road Show
symposium; November 2014
Awarded the KSS deanery
trainee bursary; September 2013 & 2016
Outstanding Poster Rosette
BSG meeting; June 2013
Travel grant awarded by the
UKINETS committee for the high standard abstract and poster presentation at the
9th UKINETS national conference; November 2011
Infection control Champion
of the Royal Free Hospital; July 2008
First prize for best junior
doctor audit; Royal Free Hospital; July 2008
Awarded the Heller Bursary
for medical humanities; The Royal Free and University College Medical School;
September 2005
Certificate of Merit for
Medicine preclinical years; The Royal Free and University College Medical
School; June 2003
ENDOSCOPIC EXPERIENCE
JETS certified for
independent OGD
JETS certified (provisional
sign-off) for colonoscopy
Emergency experience: Over
the last 5 years I have provided emergency diagnostic and therapeutic endoscopy
service in theaters, ITU and in the endoscopy department in and out of hours
Independent delivery of
endotherapy including: adrenaline injections, clip placement, variceal and GAVE
band ligation, gastric variceal gluing, APC therapy, GI tattooing, Level 1
polypectomy (<1cm), placement of endoloops, Botox injection, Haemspray
Independent placement of
PEG tubes and NG/NJ feeding tubes
Under supervision:
insertion of Sengstaken Blakemore tube, oesophageal and duodenal dilatation, GI
stenting, Level 2 polypectomy (>2cm)
CLINICAL PROCEDURES
Independently: Venepuncture, IV cannulation, arterial blood gases,
suturing and removing sutures, ascitic tap, therapeutic paracentesis, Male and
female urinary catheterisation, DC-cardioversion, external pacing, perform and
interpret ECGs, blood cultures (peripheral & central), nasogastric tube
insertion, use of local anaesthetic, intra-muscular injection, subcutaneous
injection, seroma drainage, insertion of Seldinger chest drain, aspiration of
pleural effusion, aspiration of joint effusion, lumbar puncture, insertion of
central line (US-guided and landmark technique), insertion of femoral
(US-guided and landmark technique), nasopharyngeal swabs and aspirates,
arterial line insertion, Fibroscanning of liver patients.
TEACHING EXPERIENCE
October 2015-September
2019: Simulation speciality lead for foundation year doctors; redesigned, led
and delivered the simulation teaching and training program for foundation
doctors and medical students at MediSim centre as a simulation clinical fellow;
February 2016- ongoing
Weekly simulation teaching
of medical students, foundation doctors, core medical trainees and medical
SpRs; Royal Surrey county hospital; February 2016-ongoing
IMPACT course; course tutor
and assessor. Royal Surrey County Hospital, Guildford, Surrey; May 2017
September 2017-September
2019: Editor-in-chief of the SCE gastroenterology revision resource at
https://www.studyprn.com and author of gastroenterology questions for the
Gastroenterology & Hepatology SCE
Recognised teacher status
with the University of Cardiff
September 2017- Ongoing:
Tutor & author for the postgraduate Gastroenterology Diploma course of the
University of Cardiff
€˜How to Improve Your
Teaching€™ Workshop for Higher Specialty Trainees, December 2014
Geriatric regional training
day for KSS trainees; The management of ascites and SBP Frimley Park Hospital;
July 2015
Grand Round: Evidence-based
management of ascites; Excellent feedback; Frimley Park Hospital; May 2015
Designed and led the weekly
gastroenterology teaching program at East Surrey Hospital; East Surrey &
Sussex Healthcare NHS Trust; September 2013-August 2014
Royal College associate
tutor for my Trust; East Surrey hospital; East Surrey & Sussex Healthcare
NHS Trust; September 2013-August 2014
Organised the local PACEs
teaching for East Surrey Hospital; East Surrey & Sussex Healthcare NHS
Trust Excellent student feedback. February 2014
Organised the local CMT
teaching for East Surrey Hospital. Excellent student feedback. East Surrey
& Sussex Healthcare NHS Trust; September 2013-August 2014
Gastroenterology teaching:
Final year medical students; Brighton and Sussex University Hospitals NHS
Trust; November 2013
Daily teaching on the
oncology and gastroenterology wards for UCL medical students and for doctors
revising PACES exam; Royal Free Hampstead NHS Trust, August 2011- September
2012
Official module tutor for
GIM for final year medical students; UCL medical school curriculum. Excellent
student feedback; Royal Free Hampsted NHS Trust, August 2010- September 2012
Member of the UCL support
tutor programme, which entails providing mentoring, advice and extra teaching
for individual students who have fallen behind their studies. Excellent student
feedback; Royal Free Hampstead NHS Trust; August 2010- September 2012
Designed, funded and led an
educational online project for a free revision course for doctors undergoing
MRCP Part 2 written examination; August 2010- September 2014
Medical student afterhours
teaching; Excellent student feedback; Hemel Hempstead General Hospital; August
2008- April 2009
Designed and led a 4 month
local teaching program during my attachment in breast surgery. Positive
feedback; Royal Free Hampstead NHS Trust; April 2008- August 2008
Weekly teaching on various
topics including Data interpretation and common clinical pathology. Organised
by F2 doctors; Royal Free Hampstead NHS Trust; December 2007- August 2008
Weekly teaching on various
topics including Data interpretation and common clinical pathology. Organised
by F1 doctors; Royal Free Hampstead NHS Trust; October 2007- August 2008
Completed the Teaching
Improvement Program System (TIPS) course and was one of eight people selected
to teach third year medical students as part of the Peer Assisted Learning
Scheme (PALS) at the Royal Free Hospital. Upon completing the PALS, I was
appointed as one of the official examiners for these students, who score `top
in their year; September 2006.
PUBLICATIONS
1. The role of the chronic care model
in promoting the management of the patient with rare liver disease. Pericleous
M, Kelly C, Ala A, de Lusignan S. Expert Rev Gastroenterol Hepatol. 2018 Jul 5.
doi: 10.1080/17474124.2018.1497483. [Epub ahead of print] Original Research
2. Interventions to improve the uptake
of screening across a range of conditions in Ethnic Minority Groups: a
systematic review. Kelly C, Pericleous M, Hendy J, de Lusignan S, Ahmed A,
Vandrevala T, Ala A. Int J Clin Pract. 2018 Jun 19:e13202. doi:
10.1111/ijcp.13202. [Epub ahead of print] Review.
3. Pregnancy-Associated liver disease:
A curriculum based review. Pericleous M, Kelly C (joint first authorship.
Frontline Gastroenterol. 2018 Jul;9(3):170-174
4. Wilson Disease: More Than Meets the
Eye, Pericleous M, Kelly C (joint first authorship),Postgrad Med J. 2018
Jun;94(1112):335-3472.
5. The clinical management of
hereditary haemochromatosis, Pericleous M, Kelly C (joint first authorship)
Frontline Gastroenterol. 2018 Apr;9(2):110-114.
6. Wolmans disease and cholesteryl
ester storage disorder: the phenotypic spectrum of lysosomal acid lipase
deficiency. Pericleous M, Kelly C, Wang T, Livingstone C, Ala A. Lancet
Gastroenterol Hepatol. 2017 Sep;2(9):670-679. doi:
10.1016/S2468-1253(17)30052-3.
7. The clinical management of abdominal
ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: a review
of current guidelines and recommendations. Pericleous M, Sarnowski A, Moore A,
Fijten R, Zaman M. Eur J Gastroenterol Hepatol. 2016 Mar;28(3):e10-8.
8. Outcomes of Hepatic artery
embolisation in patients with neuroendocrine tumours Pericleous M, Caplin
ME, Tsochatzis E, Yu D, Morgan-Rowe L, Toumpanakis C. Asia Pac J Clin Oncol.
2016 Mar;12(1):61-9. doi: 10.1111/ajco.12438.
9. Well-differentiated bronchial
neuroendocrine tumors: Clinical management and outcomes in 105 patients.
Pericleous M, Karpathakis A, Lumgair H, Reiner J, Toumpanakis C, Marelli L,
Thirlwell C, Meyer T, Caplin ME. Clin Respir J. 2016 Dec 27. doi:
10.1111/crj.12603.
10. Prognostic impact of novel
molecular subtypes of small intestinal neuroendocrine tumour. Karpathakis A,
Dibra H, Pipinikas C, Feber A, Morris T, Francis JM, Oukrif D, Mandair D,
Pericleous M, Mohmaduvesh M, Serra S, Ogunbiyi O, Novelli M, Luong T, Asa SL,
Kulke MH, Toumpanakis C, Meyer T, Caplin M, Meyerson M, Beck S, Thirlwell C. ;
Clin Cancer Res. 2015 Jul 13
11. Progressive epigenetic
dysregulation in neuroendocrine tumour liver metastases. Karpathakis A, Dibra
H, Pipinikas C, Feber A, Morris T, Francis J, Oukrif D, Mandair D, Pericleous
M, Mohmaduvesh M, Serra S, Ogunbiyi O, Novelli M, Luong T, Asa SL, Kulke M,
Toumpanakis C, Meyer T, Caplin M, Beck S, Thirlwell C.
12. Endocr Relat Cancer. 2017
Feb;24(2):L21-L25. doi: 10.1530/ERC-16-0419. No abstract available.
13. The Management of Acute Upper
Gastrointestinal Bleeding; a Comparison of Current Clinical Guidelines and Best
Practice Taylor A, Redfern O, Pericleous M; EMJ Gastroenterol. 2014;2
14. Outcomes Of Increased Dose Of
Allopurinol In IBD Patients Who Developed Hepatotoxicity On Low Azathioprine
And Allopurinol Co-therapy Treatment. Pericleous M, Abdulrehman A, Bull C,
Mackenzie G, Stenner J, Cowan M, Hillman G, Ansari A. Gut. 2014 Jun;63 Suppl
1:A84-5. doi: 10.1136/gutjnl-2014-307263.178.
15. Prostate cancer and the influence
of dietary factors and supplements: a systematic review.mMandair D, Rossi RE,
Pericleous M, Whyand T, Caplin ME. Nutr Metab (Lond). 2014 Jun 16;11:30. doi:
10.1186/1743-7075-11-30. eCollection 2014. Review.
16. The impact of diet and nutrition in
the prevention and progression of hepatocellular carcinoma. Mandair DS, Rossi
RE, Pericleous M, Whyand T, Caplin M. Expert Rev Gastroenterol Hepatol. 2014
May;8(4):369-82. doi: 10.1586/17474124.2014.894879. Epub 2014 Mar 6.
17. Nutrition and pancreatic cancer.
Pericleous M, Rossi RE, Mandair D, Whyand T, Caplin ME. Anticancer Res. 2014
Jan;34(1):9-21.
18. Diet and supplements and their
impact on colorectal cancer. Pericleous M, Mandair D, Caplin ME; J
Gastrointest Oncol. 2013 Dec;4(4):409-23.
19. Using an œaction set™ for the
management of acute upper gastrointestinal bleeding Pericleous M, Murray C,
Hamilton M, Epstein O, Negus R, Peachey T, Kaul A, O'Beirne J. Therap Adv
Gastroenterol. 2013 Nov;6(6):426-37.
20. Pancreatic adenocarcinoma in a
patient with multiple endocrine neoplasia 1 syndrome. Karpathakis A, Pericleous
M, Luong TV, Khoo B, Thirlwell C, Toumpanakis C, Caplin ME; Pancreas.
2013 May; 42(4):725-6.
21. Appendiceal goblet cell carcinoid
tumour: a case of unexpected lung metastasis. Pericleous M, Lumgair H, Baneke
A, Morgan-Rowe L, E Caplin M, Luong TV, Thirlwell C, Gillmore R, Toumpanakis C;
Case Rep Oncol. 2012 May;5(2):332-8
22. Gastric mixed adenoneuroendocrine
carcinoma with a trilineage cell differentiation: case report and review of the
literature. Pericleous M, Toumpanakis C, Lumgair H, Caplin ME, Morgan-Rowe L,
Clark I, Luong TV;
23. Case Rep Oncol. 2012
May;5(2):313-9.
24. Hepatobiliary disease associated
with hypereosinophilia: a report of two patients and a review of the
literature. Morgan-Rowe LM, Pericleous M, Luong TV, Dooley JS, Burroughs AK.
Dig Dis Sci. 2011 Dec;56(12):3689-94
SCIENTIFIC
MEETINGS
Regional Surrey meeting for rare liver
diseases; Guildford; October 2017
BASL international meeting 2017; Coventry;
September 2017
SESAM (Society in Europe for Simulation
Applied to Medicine); Paris, June 2017
BSG international meeting 2017; Manchester;
June 2017
AASLD international meeting; Boston; November
2016
Viral Hepatitis; State of the Art Review;
London, November 2016
Falk Symposium 205 œNew Treatment Targets in
Gut and Liver Disease; Switzerland, October 2016
BASL (British Association for the Study of the
liver) annual national meeting; Manchester; September 2016
Regional Surrey meeting for rare liver
diseases; Guildford; September 2016
Falk Symposium 204 œClinical Hepatology
Practice in 2016: from Science to Therapy; Birmingham; September 2016
Falk Symposium œAutoimmune disease of the
liver; Lisbon, May 2015
St George™s Gastroenterology training day;
London, March 2015
BVHG Meeting ˜Newer HCV Regimens “ Why, how,
when.....™; London, March 2015
Portsmouth Advanced Endoscopy Symposium;
Portsmouth, January 2015
IBS Road Show symposium; London, November 2014
Frontiers in Hepatology; London, The institute
of Hepatology, October 2014
Complex Gastroenterology; Maidstone, October
2014
Internal Medicine Research and Audit Day
(IMRAD); Brighton, September 2014
National BSG Meeting 2013 Glasgow; June 2013
National BSG-DDF Meeting; Liverpool; June 2012
9th European ENETS conference, Copenhagen;
March 2012
9th National UKINETS conference, London;
November 2011
Regional Update in Medicine; Royal Free
hospital; November 2011
Endocrinology investigations; Royal Society of
Medicine; May 2011
IBD for trainees; Royal Society of Medicine;
February 2011
Hepatology for the trainees; Royal Society of
Medicine; October 2010
Acute and general Medicine for the Physician;
3-day course at the Royal College of Physicians; October 2010
AUDIT
& CLINICAL GOVERNANCE
Replacing electrolytes in inpatients; auditing
junior doctors and development of pocket guidelines; Frimley Park Hospital NHS
Foundation Trust
PEG tubes and emergency presentations in
A&E; Frimley Park Hospital NHS Foundation Trust
Recording of OGD indications, risk scores,
endoscopic findings and endotherapy delivered in UniSoft; East Surrey &
Sussex Healthcare NHS Trust; August 2014
Waiting times from admission and diagnosis to
endoscopy in patient with upper GI bleeding; East Surrey & Sussex
Healthcare NHS Trust; July 2014
MUST scoring and nutrition screening on the
medical wards; Brighton and Sussex University Hospitals NHS Trust; August 2013
Acute management of Upper GI bleeding and the
bleeding proforma. Royal Free Hampstead NHS Trust; May 2010
Rebleed after endotherapy. Hemel Hempstead
General Hospital; February 2009
Rebleeding rates and types IV PPI
administered. Hemel Hempstead General Hospital; February 2009
Performing peripheral blood cultures Royal
Free Hampstead NHS Trust; January 2008
Down™s syndrome screening awareness in the
ethnic minorities. North Middlesex Hospital; September 2006
The effectiveness and usefulness of mnemonics
in clinical teaching. University College London; September 2006.
BOOK
CHAPTERS
1. The epidemiology of rare hereditary
metabolic liver diseases in œClinical Epidemiology of Chronic Liver Disease. Publisher: Springer Nature;
Pericleous M, Kelly C, Ala A, Schilsky M.
2. Diagnosis confirmation and screening
of Wilson disease in œManagement of Wilson Disease: A Pocket Guide. Pericleous M, Kelly C, Schilsky M.
3. Treatment options for Wilson disease
in œManagement of Wilson Disease: A Pocket Guide. Kelly C, Pericleous M, Schilsky M.
PRESENTATIONS:
ORAL, POSTER & LECTURES
Oral: Regional Surrey meeting on autoimmune
liver diseases; Guildford; October 2017
Poster: Is the chronic care model the answer
to the unmet need for integrated care in orphan liver diseases? BASL meeting;
Coventry, 2017
Poster: Interpretation of low lysosomal acid
lipase (LAL) levels in the hepatology and metabolic services; BASL meeting;
Coventry, 2017
Poster: Primary Biliary Cholangitis (PBC) - a
neglected disease in primary care? BASL meeting; Coventry, 2017
Poster: The chronic care model (CCM) in
primary biliary cholangitis (PBC): Time to reconsider our approach; BASL
meeting; Coventry, 2017
Oral presentation: œA novel approach to
simulation training for foundation year doctors; embracing new technologies and
applying learning theory; Society in Europe for Simulation Applied to Medicine (SESAM)
meeting; Paris, June 2017
Poster: What is the meaning of low lysosomal
acid lipase (LAL) levels in the hepatology and metabolic clinic? ; BSG national
meeting; Manchester, 2017
Poster: Regional and national understanding of
IgG-related disease (IgG4-RD) in the UK: Strategic implications in testing and
case-finding; American Association for the study of the liver (AASLD) annual
meeting; Boston; November 2016
Poster: Experience of IgG4-related disease
(IgG4-RD) in the UK: an online national survey; DrFalk symposium œNew Treatment
Targets in Gut and Liver Disease; Switzerland, October 2016
Poster: Trends of serum IgG4 level testing in
a UK tertiary hepatopancreatobiliary (HPB) centre and correlation with the
diagnosis of IgG4-related disease (IgG4-RD); DrFalk symposium œNew Treatment
Targets in Gut and Liver Disease; Switzerland, October 2016
Lecture: LAL deficiency and other rare diseases;
Regional Surrey meeting for rare liver diseases; Guildford; September 2016
Lecture: The management of ascites in
palliative care: 5th Guildford Advanced Pain & Symptom Management Course of
the society of palliative medicine; Guildford; September 2016
Poster: The role of repeat liver biopsy in
autoimmune hepatitis (AIH) in a tertiary HPB centre in South east England:
current experience, clinical dilemmas and recommendations; British Association
for the Study of the liver (BASL) annual meeting; Manchester; September 2016
Poster: Regional and National understanding of
IgG-related disease (IgG4-RD) in the United Kingdom: patterns of testing,
case-finding and areas for development; British Association for the Study of
the liver (BASL) annual meeting; Manchester; September 2016
Oral presentation: Regional Training Research
Networks; National BSG meeting; Liverpool 2016
Lecture: The management of ascites and SBP;
Geriatric regional training day for KSS trainees; Frimley Park Hospital; July
2015
Oral presentation: Replacing electrolytes in
inpatients: experience from a district general hospital; Buckinghamshire
Foundation Forum; Stoke Mandeville; June 2015
Lecture: Grand Round: Evidence-based
management of ascites; Frimley Park hospital; May 2015
Poster: DrFalk Symposium 2015 on Autoimmune
liver disease: Hypereosinophilic Autoimmune liver disease: A report of three
unusual cases; Lisbon; May 2015
Poster: LDAA and hepatotoxicity in IBD
patients; BSG national meeting; Manchester; June 2014
Lecture: Grand Round: 1) NETs 2) Management of
ascites; East Surrey Hospital; March 2014
Poster: TAE Vs TACE; BSG national meeting;
Glasgow, 2013
Weekly Neuroendocrine MDT preparation and
presentation; Royal Free Hospital; August 2011- September 2012
Poster: Diagnostic and therapeutic outcomes in
goblet cell appendiceal neuroendocrine tumours; National DDF & BSG joint
conference 2012: Liverpool; June 2012
Poster: Epidemiology and management outcomes
in bronchial neuroendocrine tumours: a clinical study of 116 patients;9th
European ENETS conference; Copenhagen; March 2012
Poster: 9th National UKINETS conference;
London, November 2011
Lecture: Oncology meeting of the Royal Free
Hospital: œThe patient journey: Presenting the results of my GI oncology audit; June
2011
Lecture: Cardiology Clinical Governance
meeting: Morbidity & Mortality; Royal Free Hospital; June 2011
Poster: There will be blood....a complete
audit cycle; National BSG conference 2011 meeting, Birmingham; March 2011
Poster: There will be blood; 4th International
Conference of the Society of Acute Medicine (SAM): Edinburgh; October 2010
Lecture: Grand Round presentation: œThere will
be blood, Royal Free Hospital; September 2010
Lecture: Clinical Governance meeting for acute
medicine. Presentation of my audit on the management of upper GI bleeding;
Royal Free Hospital; May 2010
Lecture: Weekly case study presentations at
the morning report; Royal Free Hospital August 2009- February 2010
Lecture: Clinical governance meeting for
gastroenterology: Presentation of my œRe-bleed after endotherapy audit; Hemel Hempstead General
Hospital; February 2009
Lecture: Department of geriatrics medical
meeting: Presented two times on the management of Multiple Myeloma and the
pathophysiology of jaundice; Hemel Hempstead General Hospital; August 2008-
December 2008:
Oral presentation: Is the incidence of
breast cancer among Asian women living in the UK, higher at a younger age than
in Caucasian women? 30th Annual International San Antonio Breast Cancer
Symposium; San Antonio, Texas, USA; December 2008:
Lecture: Weekly Oncology and breast surgery
MDT meeting: weekly preparation and presentation of meeting; Royal Free
Hampstead NHS Trust; March 2008- July 2008:
Lecture: Morbidity & Mortality meeting;
department of surgery: monthly presentations; Royal Free Hampstead NHS Trust;
March-July 2008
Lecture: Morbidity & Mortality meeting;
department of cardiology: monthly presentations; Royal Free Hampstead NHS
Trust; January 2008 “March 2008
Lecture: Audit presentation: œTaking
peripheral blood cultures; Presented to the staff of MAAU, leading consultants in infection
control and the board of trustees; Royal Free Hampstead NHS Trust; August 2008.