From Device to Disease: Tricuspid Valve Replacement in a Patient with Copper T associated Endocarditis and Thrombotic Thrombocytopenic Purpura

A Case Report | Open Access

Volume 2025 - 4 | Article ID 261 | http://dx.doi.org/10.51521/WJCRCI.2025.e41.405

From Device to Disease: Tricuspid Valve Replacement in a Patient with Copper T associated Endocarditis and Thrombotic Thrombocytopenic Purpura

Academic Editor: John Bose

Received 2025-05-22
Revised 2025-06-05
Accepted 2025-06-09
Published 2025-06-13

Nikita Mevada^a, Shubhendu Bajpai^b, Abhishek Verma^a, Visharad Trivedi^c

^aAssistant Professor, Department of Cardiac Anaesthetia, U. N. Mehta Institute of Cardiology and Research Center

^bICU Intensivist, Department of Critical Care, U. N. Mehta Institute of Cardiology and Research Center

^cAssociate Professor, Department of Cardiac Anaesthetia, U. N. Mehta Institute of Cardiology and Research Center

Corresponding author: Dr. Abhishek Verma, Assistant Professor, Department of Cardiac Anaesthetia, U. N. Mehta Institute of Cardiology and Research Center, Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat, India.

Citation: Nikita Mevada, Shubhendu Bajpai, Abhishek Verma, Visharad Trivedi (2025) From Device to Disease: Tricuspid Valve Replacement in a Patient with Copper T associated Endocarditis and Thrombotic Thrombocytopenic Purpura. World J Case Rep Clin Imag. 2025 May-June; 4(1)1-4.

Copyrights: © Dr. Abhishek Verma, et al., 2025, This article is licensed under the Creative Commons Attribution-Non Commercial-4.0-International-License-(CCBY-NC) (https://worldjournalofcasereports.org/blogpage/copyright-policy). Usage and distribution for commercial purposes require written permission.

Abstract

Background: Infective endocarditis involving the tricuspid valve is rare, typically seen in intravenous drug users or patients with indwelling vascular devices. Intrauterine device (IUD)-associated infective endocarditis is exceedingly uncommon, with very few cases documented. Even more unusual is the concomitant occurrence of thrombotic thrombocytopenic purpura (TTP), a rare and life-threatening thrombotic microangiopathy, in the setting of infective endocarditis. Here, we report a rare case of Copper T-associated tricuspid valve infective endocarditis complicated by TTP requiring surgical valve replacement and aggressive medical therapy.

Keywords: Tricuspid valve endocarditis, intrauterine device (IUD), Copper T, thrombotic thrombocytopenic purpura (TTP), infective endocarditis (IE).