Clinical Image | Open Access
Volume 2023 - 2 | Article ID 232 | http://dx.doi.org/10.51521/WJCRCI.2023.220125
Academic Editor: John Bose
P Copeland1, P Windrum1,
A Niblock1,2
1Haematology
department, Antrim Area Hospital, Northern Ireland
2School
of Medicine, Ulster University, Northern Ireland
Corresponding
Author: Aaron Niblock, Haematology Department, Antrim Area
Hospital, Northern Ireland; School of Medicine, Ulster University, Northern
Ireland
Citation: P. Copeland, P. Windrum, A. Niblock (2023). Spontaneous
Remission in a High-Grade B-Cell Lymphoma. World J Case Rep Clin Imag. 2023
October-November; 2(2)1-3.
Copyrights © 2023, Aaron Niblock, et al. This article is
licensed under the Creative Commons
Attribution-Non-Commercial-4.0-International-License-(CCBY-NC)
(https://worldjournalofcasereports.org/blogpage/copyright-policy). Usage and
distribution for commercial purposes require written permission.
Case
Presentation
A 71-year-old lady, with a background of
Rheumatoid Arthritis on methotrexate presented with fever and weight loss. Imaging revealed a liver abscess with small
volume lymphadenopathy present above and below the diaphragm.
She
was managed with IV antibiotics and cessation of methotrexate. Interestingly
the patient improved clinically however a follow-up scan 3 months later
demonstrated an increase in the size of the liver lesion to 3.5 X 2.5cm as well
as multiple enlarged nodes in the porta hepatis and peripancreatic areas. The
concern now was for an intrahepatic cholangiocarcinoma but histology was in
keeping with Diffuse Large B-Cell Lymphoma. This lesion was reviewed by numerous
pathologists. Image 1 shows the core biopsy with an infiltrate of CD20+ B cells
with a Ki67 of 60-70%. EBER ish was negative within the biopsy.
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